खांसी पर एस्ट्रोजेन का प्रभाव Influence of Estrogens on Chronic Cough

Author : Dr. PD GUPTA 

Dr. PD GUPTA Former Director Grade Scientist, Centre for Cellular and Molecular Biology, Hyderabad, India

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A chronic cough is a cough that lasts for eight weeks or more in adults and four weeks or more in children. It can be caused by a number of conditions, including infections, allergies, and lung diseases. So far as common person we know the common causes of coughing are: Allergies that involve the nose or sinuses. Asthma andChronic obstructive pulmonary disease(COPD) or chronic bronchitis). The common cold, flu, and other viral infections.However, recent research indicates a potential link between chronic cough and hormones, particularly female sex hormones like estrogen and progesterone.

Further, the observation that postmenopausalwomen suffer more withchronic cough establishes the factthat low levels of these hormones may be the one of thecauses. During periods at certain days the woman coughs more than the otherdays.This experience -- increased cough sensitivity-- is due to fluctuating hormone levels, suggesting a correlation between hormonal changes and chronic cough development. It was also proved that estrogen is thought to have protective effects on the tube connecting nose with lungs, so declining levels during menopause can lead to increased cough sensitivity. During periods it was also noticed thatcough sensitivity can vary throughout a woman's menstrual cycle, potentially due to changing estrogen and progesterone levels

Hormonal changes may affect the sensitivity of the cough reflex by influencing inflammation, mucus production, and the function of airway receptors. 

Further, it was also observed in clinical data that womensuffermore with chronic cough in compared to men, which is often attributed to the influence of sex hormones. 

While hormones can play a role, other factors heart burn, postnasal drip, and environmental triggers can also contribute to chronic cough. 

Hormonal changes might be affecting lung function and the mucous membrane of the airways, causing hypersensitivity of the cough reflex. Therefore, postmenopausal hormonal changes could play a key role in the association between increased cough and menopause.

In addition tohormones somepsychological factors such as anxiety, insomnia, somatic symptoms, social dysfunction and severe depression also the factors for casing chronic cough. (The author has his own study and views)