किस अंग में कैंसर नहीं होता : डॉ. पी.डी. गुप्ता Cancer Proof Organs in Human Body

Author : Dr. P. D.GUPTA

(Former Director Grade Scientist, Centre for Cellular and Molecular Biology, Hyderabad, India)


The growth of the body depends on cells growth and division. The cell division is controlled by the DNA present in the cell nucleus.  Old or damaged cell die, and new cells take their place. Sometimes this orderly process breaks down, and abnormal or damaged cells grow and multiply, since their organization of DNA is changed their original programme changed and the cells behave as they wish.   These cells may form tumours, which are lumps of tissue. Tumours can be cancerous or not cancerous (benign).

All cells in the adult human body come from a single cell, they should have the same properties but it is not true some acquire one function others specialised in other function, depending their position in the mass of cells. During this process some become cancer proof. It is strange but true.

Abnormal organs in the human body 

Appendix. The appendix is a small blind-ended worm-like structure at the junction of the large and the small bowel. Initially thought to be vestigial, it is now believed to be involved in being a “safe- house” for the good bacteria of the bowel, enabling them to repopulate when needed.  

Cancers. Similarly, solid cancers are not simply clones of cancer cells. Instead, they are abnormal organs composed of multiple cell types and extracellular matrix. Some aspects of tumour development resemble processes seen in developing organs, while others are more akin to tissue remodelling.   Cancer cells can also instruct surrounding tissues to undergo changes that promote malignancy.

Cancer works as organs, then why it kills a person? 

Due to uncontrolled growth, cancer cells or tumors in organs or the bloodstream can disrupt organ function.

Colon Cancer in the last stages blocks the large intestine

They may destroy healthy cells in organs, block their nutrient or oxygen supply, and allow waste products to build up. If cancer becomes severe enough that it impairs or prevents vital organ function, it can result in death.

Organs which normally will not become cancerous 

Cancer afflicts people in many parts of the body but degree of sensitivity to cancer differs from organ/tissue to tissue. Spleen cancer is far less frequent than heart cancer. The reason heart cancer occurs so seldom is that the cells in the heart don't divide – they pump the blood and that's it. The cells in the heart can divide uncontrollably and grow into cancerous tumours as they do elsewhere. It's just not that common. Due to its rarity, much less research and knowledge about this type of cancer are available. In many other tissues, like spleen, appendix also very rarely becomes cancerous.

Human eye lens tumours so far not reported though lens epithelium cells divide slow but continuously.

In contrast, following lens capsule rupture, a lens tumour can occur in other species. It is hypothesize that a genetic mechanism exists which prevents lens tumours in humans. One day when we understand by the same mechanism we can prevent other cancers too. (The author has his own study and views)